Internet Archive Search: creator:"Takai, Koji"

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Vol 11: Acyclic retinoid in chemoprevention of hepatocellular carcinoma: Targeting phosphorylated retinoid X receptor-? for prevention of liver carcinogenesis.

Oct 28, 2014 10/14

by Shimizu, Masahito; Shirakami, Yohei; Imai, Kenji; Takai, Koji; Moriwaki, Hisataka

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This article is from Journal of Carcinogenesis , volume 11 . Abstract One of the key features of hepatocellular carcinoma (HCC) is the high rate of intrahepatic recurrence that correlates with poor prognosis. Therefore, in order to improve the clinical outcome for patients with HCC, development of a chemopreventive agent that can decrease or delay the incidence of recurrence is a critical issue for urgent investigation. Acyclic retinoid (ACR), a synthetic retinoid, successfully improves HCC...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515920

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Vol 15: Impact of Serum Chemerin Levels on Liver Functional Reserves and Platelet Counts in Patients with Hepatocellular Carcinoma.

Oct 7, 2014 10/14

by Imai, Kenji; Takai, Koji; Hanai, Tatsunori; Shiraki, Makoto; Suzuki, Yusuke; Hayashi, Hideki; Naiki, Takafumi; Nishigaki, Youichi; Tomita, Eiichi; Shimizu, Masahito; Moriwaki, Hisataka

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This article is from International Journal of Molecular Sciences , volume 15 . Abstract Obesity-related metabolic abnormalities, including adipokine imbalance and chronic inflammation, are involved in liver carcinogenesis. Chemerin, a novel adipokine, plays a critical role in adipogenesis, energy metabolism, and inflammation. We evaluated the impact of serum chemerin levels on liver functional reserves in hepatocellular carcinoma (HCC) patients and on the recurrence and prognosis of HCC. This...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139783

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